Rugrats Go Wild (2003)

The Rugrats and family become stranded on an island, and Stu is blamed. The kids wander off into the jungle, and Spike loses his sense of smell due to sneezing. This becomes a problem when a clouded leopard named Siri finds out about the babies and goes after them, and the situation only gets worse when the kids become trapped underwater with an amnesic Nigel, losing oxygen fast...